A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist

IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2–4. IL-22 is produced by T cells and induces the production of acute-phase reactants in vitro and in vivo, suggesting its involvement in inflammation. Here we report the identificati...

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Библиографические подробности
Главные авторы: Xu, Wenfeng, Presnell, Scott R., Parrish-Novak, Julia, Kindsvogel, Wayne, Jaspers, Steve, Chen, Zhi, Dillon, Stacey R., Gao, Zeren, Gilbert, Teresa, Madden, Karen, Schlutsmeyer, Stacy, Yao, Lena, Whitmore, Theodore E., Chandrasekher, Yasmin, Grant, Francis J., Maurer, Mark, Jelinek, Laura, Storey, Harold, Brender, Ty, Hammond, Angie, Topouzis, Stavros, Clegg, Christopher H., Foster, Donald C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2001
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC55483/
https://ncbi.nlm.nih.gov/pubmed/11481447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171303198
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