A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist

IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2–4. IL-22 is produced by T cells and induces the production of acute-phase reactants in vitro and in vivo, suggesting its involvement in inflammation. Here we report the identificati...

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Detalhes bibliográficos
Main Authors: Xu, Wenfeng, Presnell, Scott R., Parrish-Novak, Julia, Kindsvogel, Wayne, Jaspers, Steve, Chen, Zhi, Dillon, Stacey R., Gao, Zeren, Gilbert, Teresa, Madden, Karen, Schlutsmeyer, Stacy, Yao, Lena, Whitmore, Theodore E., Chandrasekher, Yasmin, Grant, Francis J., Maurer, Mark, Jelinek, Laura, Storey, Harold, Brender, Ty, Hammond, Angie, Topouzis, Stavros, Clegg, Christopher H., Foster, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55483/
https://ncbi.nlm.nih.gov/pubmed/11481447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171303198
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