Exploiting sequence and stability information for directing nanobody stability engineering

BACKGROUND: Variable domains of camelid heavy-chain antibodies, commonly named nanobodies, have high biotechnological potential. In view of their broad range of applications in research, diagnostics and therapy, engineering their stability is of particular interest. One important aspect is the impro...

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Detaylı Bibliyografya
Yayımlandı:Biochim Biophys Acta
Asıl Yazarlar: Kunz, Patrick, Flock, Tilman, Soler, Nicolas, Zaiss, Moritz, Vincke, Cécile, Sterckx, Yann, Kastelic, Damjana, Muyldermans, Serge, Hoheisel, Jörg D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548252/
https://ncbi.nlm.nih.gov/pubmed/28642127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.06.014
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