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Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model()

Liver fibrosis and cirrhosis result from uncontrolled secretion and accumulation of extracellular matrix (ECM) proteins by hepatic stellate cells (HSCs) that are activated by liver injury and inflammation. Despite the progress in understanding the biology liver fibrogenesis and the identification of...

詳細記述

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書誌詳細
出版年:Biochem Biophys Res Commun
主要な著者: Karthikeyan, Swathi, Potter, James J., Geschwind, Jean-Francois, Sur, Surojit, Hamilton, James P., Vogelstein, Bert, Kinzler, Kenneth W., Mezey, Esteban, Ganapathy-Kanniappan, Shanmugasundaram
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548097/
https://ncbi.nlm.nih.gov/pubmed/26525850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.10.101
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