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Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model

Lack of an in vitro model of metastasis has been a major impediment in understanding the molecular regulation of metastatic processes, and identification of specific therapeutic targets. We have established an in vitro model which displayed the signatures of metastatic phenotype such as migration, i...

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Bibliografiske detaljer
Main Authors: Kunjithapatham, Rani, Karthikeyan, Swathi, Geschwind, Jean-Francois, Kieserman, Esther, Lin, MingDe, Fu, De-Xue, Ganapathy-Kanniappan, Shanmugasundaram
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212233/
https://ncbi.nlm.nih.gov/pubmed/25351825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06816
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