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A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma

Apicomplexan parasites cause serious human and animal diseases, the treatment of which requires identification of new therapeutic targets. Host-cell invasion culminates in the essential cleavage of parasite adhesins, and although the cleavage site for several adhesins maps within their transmembrane...

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Detalhes bibliográficos
Main Authors: Brossier, Fabien, Jewett, Travis J., Sibley, L. David, Urban, Sinisa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554800/
https://ncbi.nlm.nih.gov/pubmed/15753289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407918102
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