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An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion

Rhomboid proteases are membrane-embedded enzymes conserved in all kingdoms of life, but their cellular functions across evolution are largely unknown. Prior work has uncovered a role for rhomboid enzymes in host cell invasion by malaria and related intracellular parasites, but this is unlikely to be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baxt, Leigh A., Baker, Rosanna P., Singh, Upinder, Urban, Sinisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428061/
https://ncbi.nlm.nih.gov/pubmed/18559479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1667708
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