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A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma

Apicomplexan parasites cause serious human and animal diseases, the treatment of which requires identification of new therapeutic targets. Host-cell invasion culminates in the essential cleavage of parasite adhesins, and although the cleavage site for several adhesins maps within their transmembrane...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brossier, Fabien, Jewett, Travis J., Sibley, L. David, Urban, Sinisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC554800/
https://ncbi.nlm.nih.gov/pubmed/15753289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407918102
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