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Matrine increases the inhibitory effects of afatinib on H1975 cells via the IL-6/JAK1/STAT3 signaling pathway

Resistance to epidermal growth factor receptor (EGFR) inhibitors is of primary concern in the treatment of non-small-cell lung cancer (NSCLC) with EGFR mutations. To investigate the effects of matrine on H1975 cells and to examine a novel, potential treatment option for NSCLC, the present study meas...

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Publicat a:Mol Med Rep
Autors principals: Chen, Shui-Fang, Zhang, Ze-Ying, Zhang, Jian-Li
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547971/
https://ncbi.nlm.nih.gov/pubmed/28656237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6865
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