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CAFs enhance paclitaxel resistance by inducing EMT through the IL-6/JAK2/STAT3 pathway

Carcinoma-associated fibroblasts (CAFs) are the major components of mesenchymal cells in the inflammatory tumor microenvironment. They are involved in epithelial-mesenchymal transition (EMT) and chemotherapy resistance by directly contacting with cancer cells or secretory cytokines. In the present s...

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Bibliografische gegevens
Gepubliceerd in:Oncol Rep
Hoofdauteurs: Wang, Linlin, Zhang, Fang, Cui, Jian-Ying, Chen, Liang, Chen, Yue-Ting, Liu, Bo-Wen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928760/
https://ncbi.nlm.nih.gov/pubmed/29565447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6311
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