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De novo generation of antigen-specific CD4(+)CD25(+) regulatory T cells from human CD4(+)CD25(–) cells
Antigen-specificity is a hallmark of adaptive T cell-mediated immune responses. CD4(+)CD25(+)FOXP3(+) regulatory T cells (T(R)) also require activation through the T cell receptor for function. Although these cells require antigen-specific activation, they are generally able to suppress bystander T...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554797/ https://ncbi.nlm.nih.gov/pubmed/15753318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407691102 |
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