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De novo generation of antigen-specific CD4(+)CD25(+) regulatory T cells from human CD4(+)CD25(–) cells

Antigen-specificity is a hallmark of adaptive T cell-mediated immune responses. CD4(+)CD25(+)FOXP3(+) regulatory T cells (T(R)) also require activation through the T cell receptor for function. Although these cells require antigen-specific activation, they are generally able to suppress bystander T...

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Autors principals: Walker, Mindi R., Carson, Bryan D., Nepom, Gerald T., Ziegler, Steven F., Buckner, Jane H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC554797/
https://ncbi.nlm.nih.gov/pubmed/15753318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407691102
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