Lentivirus-mediated RIG-I knockdown relieves cell proliferation inhibition, cell cycle arrest and apoptosis in ATRA-induced NB4 cells via the AKT-FOXO3A signaling pathway in vitro

Retinoic acid inducible gene I (RIG-I) is upregulated during all-trans retinoic acid (ATRA)-induced terminal granulocytic differentiation of NB4 acute promyelocytic leukemia (APL) cells. However, the function and mechanism of RIG-I in NB4 cells remains to be fully elucidated. In the present study, l...

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Publicado no:Mol Med Rep
Main Authors: Chen, Lei, Cui, Ya-Bin, Si, Yu-Ling, Su, Wei-Dong, Wang, Xin-Chao, Pang, Hua, Qiu, Li-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547964/
https://ncbi.nlm.nih.gov/pubmed/28656276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6858
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