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Icariside II induces cell cycle arrest and apoptosis in human glioblastoma cells through suppressing Akt activation and potentiating FOXO3a activity

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and currently chemotherapeutic options for GBM are very limited. Given the poor prognosis, the development of novel anti-GBM agents is quite urgent. Using two human glioma cells (U87 and A172 cells), we demonstrated that...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Quan, Kai, Zhang, Xin, Fan, Kun, Liu, Peixi, Yue, Qi, Li, Bo, Wu, Jinfeng, Liu, Baojun, Xu, Yang, Hua, Wei, Zhu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446533/
https://ncbi.nlm.nih.gov/pubmed/28560001
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