Knockdown of SIRT1 Suppresses Bladder Cancer Cell Proliferation and Migration and Induces Cell Cycle Arrest and Antioxidant Response through FOXO3a-Mediated Pathways

Bladder cancer (BCa) is one of the most common tumors, but its underlying mechanism has not been fully clarified. Our transcriptome analysis suggested a close link of Sirtuins, Peroxisome Proliferator-Activated Receptor (PPAR), cell cycle regulation, reactive oxygen species (ROS) metabolism, and For...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Hu, Qingxuan, Wang, Gang, Peng, Jianping, Qian, Guofeng, Jiang, Wei, Xie, Conghua, Xiao, Yu, Wang, Xinghuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632854/
https://ncbi.nlm.nih.gov/pubmed/29147649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3781904
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