Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway

Simvastatin is currently one of the most common drugs for old patients with hyperlipidemia, hypercholesterolemia and atherosclerotic diseases by reducing cholesterol level and anti-lipid properties. Importantly, simvastatin has also been reported to have anti-tumor effect, but the underlying mechani...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Gang, Cao, Rui, Wang, Yongzhi, Qian, Guofeng, Dan, Han C., Jiang, Wei, Ju, Lingao, Wu, Min, Xiao, Yu, Wang, Xinghuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078845/
https://ncbi.nlm.nih.gov/pubmed/27779188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35783
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