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De novo peptide sequencing by deep learning

De novo peptide sequencing from tandem MS data is the key technology in proteomics for the characterization of proteins, especially for new sequences, such as mAbs. In this study, we propose a deep neural network model, DeepNovo, for de novo peptide sequencing. DeepNovo architecture combines recent...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tran, Ngoc Hieu, Zhang, Xianglilan, Xin, Lei, Shan, Baozhen, Li, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547637/
https://ncbi.nlm.nih.gov/pubmed/28720701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705691114
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