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Cytosolic interaction of type III human CD38 with CIB1 modulates cellular cyclic ADP-ribose levels
CD38 catalyzes the synthesis of the Ca(2+) messenger, cyclic ADP-ribose (cADPR). It is generally considered to be a type II protein with the catalytic domain facing outside. How it can catalyze the synthesis of intracellular cADPR that targets the endoplasmic Ca(2+) stores has not been resolved. We...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547619/ https://ncbi.nlm.nih.gov/pubmed/28720704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703718114 |
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