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Cytosolic interaction of type III human CD38 with CIB1 modulates cellular cyclic ADP-ribose levels

CD38 catalyzes the synthesis of the Ca(2+) messenger, cyclic ADP-ribose (cADPR). It is generally considered to be a type II protein with the catalytic domain facing outside. How it can catalyze the synthesis of intracellular cADPR that targets the endoplasmic Ca(2+) stores has not been resolved. We...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Jun, Zhao, Yong Juan, Li, Wan Hua, Hou, Yun Nan, Li, Ting, Zhao, Zhi Ying, Fang, Cheng, Li, Song Lu, Lee, Hon Cheung
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547619/
https://ncbi.nlm.nih.gov/pubmed/28720704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703718114
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