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Cytosolic CD38 Protein Forms Intact Disulfides and Is Active in Elevating Intracellular Cyclic ADP-ribose

CD38 catalyzes the synthesis of cyclic ADP-ribose (cADPR), a Ca(2+) messenger responsible for regulating a wide range of physiological functions. It is generally regarded as an ectoenzyme, but its intracellular localization has also been well documented. It is not known if internal CD38 is enzymatic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Yong Juan, Zhang, Hong Min, Lam, Connie Mo Ching, Hao, Quan, Lee, Hon Cheung
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121361/
https://ncbi.nlm.nih.gov/pubmed/21524995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.228379
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