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Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin

Thyroid hormone receptors (TRs) are members of the nuclear hormone receptor superfamily that act as ligand-dependent transcription factors. Here we identified the ten-eleven translocation protein 3 (TET3) as a TR interacting protein increasing cell sensitivity to T3. The interaction between TET3 and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Guan, Wenyue, Guyot, Romain, Samarut, Jacques, Flamant, Frédéric, Wong, Jiemin, Gauthier, Karine Cécile
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547603/
https://ncbi.nlm.nih.gov/pubmed/28716910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702192114
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