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Low O(2) tensions and the prevention of differentiation of hES cells

Early-stage mammalian embryos develop in a low O(2) environment (hypoxia). hES cells, however, are generally cultured under an atmosphere of 21% O(2) (normoxia), under which conditions they tend to differentiate spontaneously. Such conditions may not be the most suitable, therefore, for hES cell pro...

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Detalhes bibliográficos
Main Authors: Ezashi, Toshihiko, Das, Padmalaya, Roberts, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554750/
https://ncbi.nlm.nih.gov/pubmed/15772165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501283102
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