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Combinatorial Roles of Protein Kinase A, Ets2, and 3′,5′-Cyclic-Adenosine Monophosphate Response Element-Binding Protein-Binding Protein/p300 in the Transcriptional Control of Interferon-τ Expression in a Trophoblast Cell Line

In ruminants, conceptus interferon-τ (IFNT) production is necessary for maintenance of pregnancy. We examined the role of protein kinase A (PKA) in regulating IFNT expression through the activation of Ets2 in JAr choriocarcinoma cells. Although overexpression of the catalytic subunit of PKA or the a...

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Detalhes bibliográficos
Main Authors: Das, Padmalaya, Ezashi, Toshihiko, Gupta, Rangan, Roberts, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234587/
https://ncbi.nlm.nih.gov/pubmed/17975022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0300
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