EFFECTS OF FGF2 AND OXYGEN IN THE BMP4-DRIVEN DIFFERENTIATION OF TROPHOBLAST FROM HUMAN EMBRYONIC STEM CELLS

Human embryonic stem cells (hESC) differentiate into trophoblast when treated with BMP4. Here we studied the effects of either low (4 % O(2), L) or atmospheric O(2) (20% O(2), A) in the presence and absence of FGF2 on H1 hESC cultured in presence of BMP4. Differentiation progressed from the peripher...

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Détails bibliographiques
Auteurs principaux: Das, Padmalaya, Ezashi, Toshihiko, Schulz, Laura C., Westfall, Suzanne D., Livingston, Kimberly A., Roberts, R. Michael
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634289/
https://ncbi.nlm.nih.gov/pubmed/19194525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2007.09.004
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