Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem Cells

To realize the full potential of human embryonic stem cells (hESCs), it is important to develop culture conditions that maintain hESCs in a pluripotent, undifferentiated state. A low O(2) atmosphere (∼4% O(2)), for example, prevents spontaneous differentiation and supports self-renewal of hESCs. To...

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Detalhes bibliográficos
Main Authors: Westfall, Suzanne D., Sachdev, Shrikesh, Das, Padmalaya, Hearne, Leonard B., Hannink, Mark, Roberts, R. Michael, Ezashi, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189708/
https://ncbi.nlm.nih.gov/pubmed/18811242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2007.0240
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