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Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis
Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder resulting from mutations in the dystrophin gene. The mdx/utrn (−/−) mouse, lacking in both dystrophin and its autosomal homologue utrophin, is commonly used to model the clinical symptoms of DMD. Interestingly, these mice are infertil...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547154/ https://ncbi.nlm.nih.gov/pubmed/28785010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05993-8 |
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