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The Nuclear Orphan Receptor NR4A1 Regulates β1-Integrin Expression in Pancreatic and Colon Cancer Cells and Can Be Targeted by NR4A1 Antagonists

β1-Integrin is highly expressed and is a negative prognostic factor for colon and pancreatic cancer patients and the gene plays a functional role in cell migration and invasion. In this study, we demonstrate that β1-integrin expression is regulated in pancreatic and colon cancer cells by the pro-onc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Carcinog
Hauptverfasser: Hedrick, Erik, Lee, Syng-ook, Safe, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546981/
https://ncbi.nlm.nih.gov/pubmed/28418095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22662
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