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β Cells Persist in T1D Pancreata Without Evidence of Ongoing β-Cell Turnover or Neogenesis

CONTEXT: The cellular basis of persistent β-cell function in type 1 diabetes (T1D) remains enigmatic. No extensive quantitative β-cell studies of T1D pancreata have been performed to test for ongoing β-cell regeneration or neogenesis. OBJECTIVE: We sought to determine the mechanism of β-cell persist...

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Foilsithe in:J Clin Endocrinol Metab
Main Authors: Lam, Carol J., Jacobson, Daniel R., Rankin, Matthew M., Cox, Aaron R., Kushner, Jake A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Endocrine Society 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546851/
https://ncbi.nlm.nih.gov/pubmed/28323930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3806
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