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Sequential neuromodulation of Hebbian plasticity offers mechanism for effective reward-based navigation

Spike timing-dependent plasticity (STDP) is under neuromodulatory control, which is correlated with distinct behavioral states. Previously, we reported that dopamine, a reward signal, broadens the time window for synaptic potentiation and modulates the outcome of hippocampal STDP even when applied a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Brzosko, Zuzanna, Zannone, Sara, Schultz, Wolfram, Clopath, Claudia, Paulsen, Ole
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546805/
https://ncbi.nlm.nih.gov/pubmed/28691903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27756
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