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Retroactive modulation of spike timing-dependent plasticity by dopamine

Most reinforcement learning models assume that the reward signal arrives after the activity that led to the reward, placing constraints on the possible underlying cellular mechanisms. Here we show that dopamine, a positive reinforcement signal, can retroactively convert hippocampal timing-dependent...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Brzosko, Zuzanna, Schultz, Wolfram, Paulsen, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626806/
https://ncbi.nlm.nih.gov/pubmed/26516682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09685
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