New variants of inducible Cre recombinase: a novel mutant of Cre–PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility

We have developed a novel inducible Cre mutant with enhanced recombinase activity to mediate genetic switching events. The protein, designated Cre*PR, is composed of a new Cre mutant at the N-terminus followed by the ligand-binding domain (LBD) of the progesterone receptor (PR). The response to low...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Wunderlich, Frank T., Wildner, Hendrik, Rajewsky, Klaus, Edenhofer, Frank
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	NAR Methods Online
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353092/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.10.e47
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