Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells

Tumor hypoxia promotes neoangiogenesis and contributes to the radio- and chemotherapy resistant and aggressive phenotype of cancer cells. However, the migratory response of tumor cells and the role of small GTPases regulating the organization of cytoskeleton under hypoxic conditions have yet to be e...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Tátrai, Enikő, Bartal, Alexandra, Gacs, Alexandra, Paku, Sándor, Kenessey, István, Garay, Tamás, Hegedűs, Balázs, Molnár, Eszter, Cserepes, Mihály T., Hegedűs, Zita, Kucsma, Nóra, Szakács, Gergely, Tóvári, József
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546497/
https://ncbi.nlm.nih.gov/pubmed/28562340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17806
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