Prenylation Inhibition-Induced Cell Death in Melanoma: Reduced Sensitivity in BRAF Mutant/PTEN Wild-Type Melanoma Cells

While targeted therapy brought a new era in the treatment of BRAF mutant melanoma, therapeutic options for non-BRAF mutant cases are still limited. In order to explore the antitumor activity of prenylation inhibition we investigated the response to zoledronic acid treatment in thirteen human melanom...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garay, Tamás, Kenessey, István, Molnár, Eszter, Juhász, Éva, Réti, Andrea, László, Viktória, Rózsás, Anita, Dobos, Judit, Döme, Balázs, Berger, Walter, Klepetko, Walter, Tóvári, József, Tímár, József, Hegedűs, Balázs
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315579/
https://ncbi.nlm.nih.gov/pubmed/25646931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117021
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