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Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

A large body of evidence supports an important role for calcitonin gene-related peptide (CGRP) in migraine pathophysiology. This evidence gave rise to a global effort to develop a new generation of therapeutics that inhibit the interaction of CGRP with its receptor in migraineurs. Recently, a new cl...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Melo-Carrillo, Agustin, Noseda, Rodrigo, Nir, Rony, Schain, Aaron J., Stratton, Jennifer, Strassman, Andrew M., Burstein, Rami
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546397/
https://ncbi.nlm.nih.gov/pubmed/28642283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0576-17.2017
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