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Aβ-Specific Th2 cells Provide Cognitive and Pathological Benefits to Alzheimer’s Mice without Infiltrating the CNS
We have found that a small number of purified Th2-biased Aβ-specific T cells are sufficient to provide profound cognitive and pathological benefits in an APP+PS1 mouse model for Alzheimer’s disease. Six weeks after receiving T cell infusions, cognitively-impaired mice performed significantly better...
में बचाया:
| में प्रकाशित: | Neurobiol Dis |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546306/ https://ncbi.nlm.nih.gov/pubmed/19167499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.12.015 |
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