Wird geladen...

HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease

Transplantation of neural stem cells (NSCs) can improve cognition in animal models of Alzheimer's disease (AD). However, AD is a protracted disorder, and prior studies have examined only short-term effects. We therefore used an immune-deficient model of AD (Rag-5xfAD mice) to examine long-term...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Marsh, Samuel E., Yeung, Stephen T., Torres, Maria, Lau, Lydia, Davis, Joy L., Monuki, Edwin S., Poon, Wayne W., Blurton-Jones, Mathew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312253/
https://ncbi.nlm.nih.gov/pubmed/28199828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.12.019
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!