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Systemic ATP impairs neutrophil chemotaxis and host defense in sepsis
OBJECTIVE: Sepsis remains an unresolved clinical problem. Therapeutic strategies focusing on inhibition of neutrophils (PMNs) have failed, which indicates that a more detailed understanding of the underlying pathophysiology of sepsis is required. PMN activation and chemotaxis require cellular ATP re...
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| Publicado no: | Crit Care Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546305/ https://ncbi.nlm.nih.gov/pubmed/27548819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000002052 |
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