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Atypical dopamine transporter inhibitors R-modafinil and JHW 007 differentially affect D2 autoreceptor neurotransmission and the firing rate of midbrain dopamine neurons

Abuse of psychostimulants like cocaine that inhibit dopamine (DA) reuptake through the dopamine transporter (DAT) represents a major public health issue, however FDA-approved pharmacotherapies have yet to be developed. Recently a class of ligands termed “atypical DAT inhibitors” has gained attention...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Avelar, Alicia J., Cao, J., Newman, Amy Hauck, Beckstead, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546153/
https://ncbi.nlm.nih.gov/pubmed/28625719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.06.016
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