Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells

Cancer cells are immature cells resulting from cellular reprogramming by gene misregulation, and redifferentiation is expected to reduce malignancy. It is unclear, however, whether cancer cells can undergo terminal differentiation. Here, we show that inhibition of the epigenetic modification enzyme...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Zan, Lei, Anhua, Xu, Liyang, Chen, Lu, Chen, Yonglong, Zhang, Xuena, Gao, Yan, Yang, Xiaoli, Zhang, Min, Cao, Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546026/
https://ncbi.nlm.nih.gov/pubmed/28634230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785865
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