Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells

Cancer cells are immature cells resulting from cellular reprogramming by gene misregulation, and redifferentiation is expected to reduce malignancy. It is unclear, however, whether cancer cells can undergo terminal differentiation. Here, we show that inhibition of the epigenetic modification enzyme...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Zan, Lei, Anhua, Xu, Liyang, Chen, Lu, Chen, Yonglong, Zhang, Xuena, Gao, Yan, Yang, Xiaoli, Zhang, Min, Cao, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546026/
https://ncbi.nlm.nih.gov/pubmed/28634230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785865
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