Cardiac myocyte p38α kinase regulates angiogenesis via myocyte-endothelial cell cross-talk during stress-induced remodeling in the heart

Stress-induced p38 mitogen-activated protein kinase (MAPK) activity is implicated in pathological remodeling in the heart. For example, constitutive p38 MAPK activation in cardiomyocytes induces pathological features, including myocyte hypertrophy, apoptosis, contractile dysfunction, and fetal gene...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Rose, Beth A., Yokota, Tomohiro, Chintalgattu, Vishnu, Ren, Shuxun, Iruela-Arispe, Luisa, Khakoo, Aarif Y., Minamisawa, Susumu, Wang, Yibin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546022/
https://ncbi.nlm.nih.gov/pubmed/28637870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.784553
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