alpha-Thrombin-induced early mitogenic signalling events and G0 to S-phase transition of fibroblasts require continual external stimulation.

In resting Chinese hamster fibroblasts (CCL39) alpha-thrombin rapidly stimulates several biochemical events implicated in the mitogenic response, including the breakdown of inositol phospholipids, activation of a plasma membrane Na+/H+ antiporter, phosphorylation of ribosomal protein S6 and increase...

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Bibliographic Details
Main Authors: Van Obberghen-Schilling, E, Chambard, J C, Paris, S, L'Allemain, G, Pouysségur, J
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC554600/
https://ncbi.nlm.nih.gov/pubmed/2998766
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