alpha-Thrombin-induced early mitogenic signalling events and G0 to S-phase transition of fibroblasts require continual external stimulation.

In resting Chinese hamster fibroblasts (CCL39) alpha-thrombin rapidly stimulates several biochemical events implicated in the mitogenic response, including the breakdown of inositol phospholipids, activation of a plasma membrane Na+/H+ antiporter, phosphorylation of ribosomal protein S6 and increase...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Van Obberghen-Schilling, E, Chambard, J C, Paris, S, L'Allemain, G, Pouysségur, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2998766/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb04025.x
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