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Transferrin-Dressed Virus-like Ternary Nanoparticles with Aggregation-Induced Emission for Targeted Delivery and Rapid Cytosolic Release of siRNA

Viruses have evolved to be outstandingly efficient at gene delivery, but their use as vectors is limited by safety risks. Inspired by the structure of viruses, we constructed a virus-mimicking vector (denoted as TR4@siRNA@Tf NCs) with virus-like architecture and infection properties. Composed of a h...

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Detalhes bibliográficos
Publicado no:ACS Appl Mater Interfaces
Main Authors: Zhang, Tingbin, Guo, Weisheng, Zhang, Chunqiu, Yu, Jing, Xu, Jing, Li, Shuyi, Tian, Jian-Hua, Wang, Paul C., Xing, Jin-Feng, Liang, Xing-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545884/
https://ncbi.nlm.nih.gov/pubmed/28447465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.7b03402
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