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Antisense oligonucleotides selected by hybridisation to scanning arrays are effective reagents in vivo

Transcripts representing mRNAs of three Xenopus cyclins, B1, B4 and B5, were hybridised to arrays of oligonucleotides scanning the first 120 nt of the coding region to assess the ability of the immobilised oligonucleotides to form heteroduplexes with their targets. Oligonucleotides that produced hig...

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Main Authors: Sohail, Muhammad, Hochegger, Helfrid, Klotzbücher, Andrea, Guellec, Rene Le, Hunt, Tim, Southern, Edwin M.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC55457/
https://ncbi.nlm.nih.gov/pubmed/11353073
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