Inhibition of calf thymus type II DNA topoisomerase by poly(ADP-ribosylation).

The effect of poly(ADP-ribosylation) on calf thymus topoisomerase type II reactions has been investigated. Unknotting of phage P4 head DNA, and relaxation and catenation of supercoiled PM2 DNA are inhibited. We conclude that the inhibition results from poly(ADP-ribosylation) on the following grounds...

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Publicat a:EMBO J
Autors principals: Darby, M K, Schmitt, B, Jongstra-Bilen, J, Vosberg, H P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1985
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2998783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03903.x
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