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Inhibition of calf thymus type II DNA topoisomerase by poly(ADP-ribosylation).

The effect of poly(ADP-ribosylation) on calf thymus topoisomerase type II reactions has been investigated. Unknotting of phage P4 head DNA, and relaxation and catenation of supercoiled PM2 DNA are inhibited. We conclude that the inhibition results from poly(ADP-ribosylation) on the following grounds...

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Detalhes bibliográficos
Main Authors: Darby, M K, Schmitt, B, Jongstra-Bilen, J, Vosberg, H P
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554473/
https://ncbi.nlm.nih.gov/pubmed/2998783
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