Generation of Myostatin Gene-Edited Channel Catfish (Ictalurus punctatus) via Zygote Injection of CRISPR/Cas9 System

The myostatin (MSTN) gene is important because of its role in regulation of skeletal muscle growth in all vertebrates. In this study, CRISPR/Cas9 was utilized to successfully target the channel catfish, Ictalurus punctatus, muscle suppressor gene MSTN. CRISPR/Cas9 induced high rates (88–100%) of mut...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Khalil, Karim, Elayat, Medhat, Khalifa, Elsayed, Daghash, Samer, Elaswad, Ahmed, Miller, Michael, Abdelrahman, Hisham, Ye, Zhi, Odin, Ramjie, Drescher, David, Vo, Khoi, Gosh, Kamal, Bugg, William, Robinson, Dalton, Dunham, Rex
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544710/
https://ncbi.nlm.nih.gov/pubmed/28779173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07223-7
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