Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease

Increasing evidence shows that metabolic abnormalities in body fluids are distinguishing features of the pathophysiology of Parkinson’s disease. However, a non-invasive approach has not been established in the earliest or pre-symptomatic phases. Here, we report comprehensive double-cohort analyses o...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Saiki, Shinji, Hatano, Taku, Fujimaki, Motoki, Ishikawa, Kei-Ichi, Mori, Akio, Oji, Yutaka, Okuzumi, Ayami, Fukuhara, Takeshi, Koinuma, Takahiro, Imamichi, Yoko, Nagumo, Miho, Furuya, Norihiko, Nojiri, Shuko, Amo, Taku, Yamashiro, Kazuo, Hattori, Nobutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544708/
https://ncbi.nlm.nih.gov/pubmed/28779141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06767-y
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