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Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions

Iron is an essential nutrient for mitochondrial metabolic processes, including mitochondrial respiration. Ferritin complexes store excess iron and protect cells from iron toxicity. Therefore, iron stored in the ferritin complex might be utilized under iron-depleted conditions. In this study, we show...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Fujimaki, Motoki, Furuya, Norihiko, Saiki, Shinji, Amo, Taku, Imamichi, Yoko, Hattori, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597882/
https://ncbi.nlm.nih.gov/pubmed/31061094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00010-19
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