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Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions

Iron is an essential nutrient for mitochondrial metabolic processes, including mitochondrial respiration. Ferritin complexes store excess iron and protect cells from iron toxicity. Therefore, iron stored in the ferritin complex might be utilized under iron-depleted conditions. In this study, we show...

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Pubblicato in:Mol Cell Biol
Autori principali: Fujimaki, Motoki, Furuya, Norihiko, Saiki, Shinji, Amo, Taku, Imamichi, Yoko, Hattori, Nobutaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597882/
https://ncbi.nlm.nih.gov/pubmed/31061094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00010-19
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