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Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions

Iron is an essential nutrient for mitochondrial metabolic processes, including mitochondrial respiration. Ferritin complexes store excess iron and protect cells from iron toxicity. Therefore, iron stored in the ferritin complex might be utilized under iron-depleted conditions. In this study, we show...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Fujimaki, Motoki, Furuya, Norihiko, Saiki, Shinji, Amo, Taku, Imamichi, Yoko, Hattori, Nobutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597882/
https://ncbi.nlm.nih.gov/pubmed/31061094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00010-19
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