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Stable membrane orientations of small dual-topology membrane proteins

The topologies of α-helical membrane proteins are generally thought to be determined during their cotranslational insertion into the membrane. It is typically assumed that membrane topologies remain static after this process has ended. Recent findings, however, question this static view by suggestin...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Fluman, Nir, Tobiasson, Victor, von Heijne, Gunnar
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544329/
https://ncbi.nlm.nih.gov/pubmed/28698365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706905114
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